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Nomenclature: CB17.Cg-PrkdcscidHrhr/IcrCrl
Type: Congenic, Immunodeficient
Origin: The hairless SCID congenic was created in 2009 by Charles River Research Models by using marker-assisted accelerated backcrossing to place the hairless gene (Hrhr) present in the Crl:SKH1-Hrhr stock onto a CB17/Icr-Prkdcscid/IcrIcoCr genetic background. These mice are homozygous for both Hrhr and Prkdcscid mutations, so exhibit the severe combined immunodeficiency phenotype characteristic of SCID mice and are also hairless.
See Charles River webpage with resources about immunodeficient models: Immunodeficient Mice and Rats
Coat color: Hairless, albino background
Strain code: 488

