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Nomenclature: Crl:CD1-Foxn1nu
Type: Outbred, Immunodeficient
Origin: Developed from the transfer of the nude gene from Crl:NU-Foxn1nu to a CD-1® mouse through a series of crosses and backcrosses beginning in 1979 at Charles River Laboratories, Wilmington, MA. The animal lacks a thymus, is unable to produce T-cells, and is therefore immunodeficient.
The control model for the CD-1® Nude mouse is the CD-1® Heterozygous mouse.
See Charles River webpage with resources about immunodeficient models: Immunodeficient Mice and Rats
Coat color: Hairless, albino background (Homozygous), White, albino (Heterozygous)
Strain code: 086 (Homozygous), 087 (Heterozygous)
Ideal for: Tumor biology and xenograft research

