BioLASCO Taiwan Co., Ltd.
3F., No. 267, Chongyang Rd., Nangang Dist., Taipei City, , Taiwan (R.O.C.)
Tel:(02) 2651-8669
Fax:(02) 2651 – 8969
LAL Kinetic Chromogenic Assay
Limulus amebocyte lysate (LAL), an aqueous extract derived from Limulus amebocytes, which is intended for quantitative detection of endotoxins by the Gel-clot methods. Improvements in LAL reagents, the advent of standard methods and automated systems, and a better understanding of LAL reactivity make the LAL reagent readily adaptable to testing a variety of biologics, parenteral products and medical devices. Currently, endotoxin detection methods based on lysate reagents include the Gel-Clot, Turbidimetric assay, and Chromogenic assay.
CRL Endosafe® endotoxin testing reagent has been approved by the FDA. Our gel clot endotoxin test lysate features a firm gel over a wide range of sensitivities, designed with advanced formulations to provide better interference resistance and higher accuracy for routine LAL testing.
Kinetic Chromogenic Reagents
The principle is similar to the turbidimetric method. A chromogenic substrate is added to the reagent, the enzymatic reaction will cause a yellow color to develop upon cleavage of the chromophore, p-nitroaniline (pNA). pNA liberation can be measured spectrophotometrically. Endochrome-K LAL provides heightened sensitivity for more accurate results, greater linearity for endotoxin analyses, and superior interference resistance.
| Kinetic Chromogenic Reagents | Sensitivity (EU/mL) | Code | Format |
| Endochrome-KTM | 0.005 | R17100 |
Box of 100 |
Control Standard
The E. coli CSE is a validated positive control, standardized and quantified using the U.S. Reference Standard Endotoxin. For detailed verification, please refer to the Certificate of Analysis (CoA).
| Control Standard Endotoxin | Code | Format |
| CSE-10 ng per vial | E120 | Pack of 6 |
| CSE-500 ng per vial | E110 | Pack of 6 |
| Reference standard endotoxin (RSE) | E150 | ─ |
LAL Reagent Water
To prevent contamination, all accessories and consumables must be endotoxin-free. Reagents and test samples should be prepared using endotoxin-free water for bacterial endotoxin testing.
| LAL Reagent Water | Code | Format |
| 50 mL bottle | W120 | 12瓶/盒 |
| 100 mL bottle | W110 | 12瓶/盒 |
| 500 mL bottle | W150 | 6瓶/盒 |
* Endotoxin Test Result : < 0.001 EU/mL.